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Injectable Steroids Tacrolimus CAS 104987-11-3 For Immune Suppressant
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1.Quick Detail:
Product Name:Tacrolimus
Purity: 99%
CAS: 104987-11-3
MF: C44H69NO12
MW: 804.02
Appearance: White powder
Storage: Store in a cool, dry place. Do not store in direct sunlight. Store in a tightly closed container.
2.Tacrolimus Description:
"Tacrolimus" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH. Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.A macrolide isolated from the culture broth of a strain of Streptomyces tsukubaensis that has strong immunosuppressive activity in vivo and prevents the activation of T-lymphocytes in response to antigenic or mitogenic stimulation in vitro.
Tacrolimus (also FK-506 or Fujimycin) is an immunosuppressive drug whose main use is after organ transplant to reduce the activity of the patient’s immune system and so the risk of organ rejection. It is also used in a topical preparation in the treatment of severe atopic dermatitis, severe refractory uveitis after bone marrow transplants, and the skin condition vitiligo.
Tacrolimus is chemically known as a macrolide. It reduces peptidyl-prolyl isomerase activity by binding to the immunophilin FKBP-12 (FK506 binding protein) creating a new complex. This FKBP12-FK506 complex interacts with and inhibits calcineurin thus inhibiting both T-lymphocyte signal transduction and IL-2 transcription.
3.Product Usage:
Tacrolimus is used together with other medicines to prevent the body from rejecting a transplanted organ (eg, kidney, liver, or heart). This medicine may be used with steroids, azathioprine, basiliximab, or mycophenolate mofetil. Tacrolimus belongs to a group of medicines known as immunosuppressive agents.
Tacrolimus is a very strong medicine. It can cause side effects that can be very serious, such as kidney problems. It may also decrease the body's ability to fight infections. You and your doctor should talk about the benefits of this medicine as well as the risks of using it.
Tacroz Forte Ointment (Tacrolimus) is used to treat atopic dermatitis (more commonly known as eczema). It is a topical medication which is normally prescribed for patients who have not responded successfully to other eczema medication.
The ointment is a type of topical calcineurin inhibitor (TCIs) that works by weakening the patient`s immune system, which as a consequence directly reduces the severity of eczema and its symptoms. It should not be used by patients who have any kind of weak immune system.
4.Competitive Advantage:
Rich experience.
Having been specialized in this field for years, we have rich experience and widespread sales network around the word. Our steroid and hormones have been exported to overseas, like Europe, Africa, Asia, America and other countries. We are not got good feedback from our guest, but also established long business relationship with them.
Great quality and high purity.
Good quality is one secret for our success. All of our products enjoys high purity. Thus, it can make sure our client's need. Welcome order the samples, MOQ just 10 grams.
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