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CAS 67392-87-4 Drospirenone

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CAS 67392-87-4 Drospirenone

What is Drospirenone?

Drospirenone is a progestin medication which is used in birth control pills and in menopausal hormone therapy. The medication is available only in combination with an estrogen.

Drospirenone is a synthetic progestin that is an analog to spironolactone. It is found in a number of birth control formulations. Drospirenone differs from other synthetic progestins in that its pharmacological profile in preclinical studies shows it to be closer to the natural progesterone. As such it has anti-mineralocorticoid properties, counteracts the estrogen-stimulated activity of the renin-angiotensin-aldosterone system, and is not androgenic. It was shown in animal studies that drospirenone exhibits antiandrogenic activity judging from accessory sex gland growth in castrated, androgen-treated, juvenile rats.


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