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Tretinoin CAS 302-79-4, also known as Vitamin A Acid, Retinoids, is an oral pharmaceutical drug primarily used to treatsevere nodular acne. Rarely, it is also used to prevent certain skin cancers (squamous-cell carcinoma), and in the treatment of other cancers. It is used to treat harlequin-type ichthyosis, a usually lethal skin disease, and lamellar ichthyosis.
SpecificationDescription: Yellow crystalline powder
Assay: 98.0-102.0%
Standard: USP26/28,EP5
Application
It can rapidly and strongly inhibit the cell proliferation and differentiation process of skin glands cells. It has a high effect on severe nodular cystic acne. This product has a high gastrointestinal absorption, but invalid for topical administration.
It may also reduce the volume of the sebaceous glands, reducing the skin's DHT, down-regulate the expression of skin androgen receptor. Other possible mechanism includes reducing the hair follicle keratosis, antibacterial, anti-inflammatory effects and so on.
Sodium Erythorbate Specification:
|
|
STANDARD | |
| ITEM | GB8273-2008 | FCCV |
| Exterior | White or a slightly yellow crystalline pellet or powder | White,odorless,crystalline powder or granules |
| Assay | >98.0% | 98.0%-100.5% |
| Specific Rotation | +95.5°~+98.0° | +95.5°~+98.0° |
| Clarity | Up to standard | Up to standard |
| PH | 5.5-8.0 | 5.5-8.0 |
| Heavy metal(Pb) | <0.002% | <0.001% |
| Lead | ---- | <0.0005% |
| Arsenic | <0.0003% | <0.0003% |
| Oxalatc | Up to standard | Up to standard |
| Indentification | ----- | Passed test |
| Loss on drying | ------ | ≤0.25% |
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