Indomethacin CAS:53-86-1

Indomethacin
Another Name:2-methyl-1-(4-chloro-benzoyl)-5-methoxy-1H-indole-3 -acetic acid
CAS:53-86-1
Molecular Weight:357.79
Molecular Formula:C19H16CINO4
Traits: powder
Uses:
(1)arthritis, can relieve pain and swelling.
(2)soft tissue damage and inflammation;
(3)antipyretic;
(4)other: for the treatment of migraine, dysmenorrhea, post-operative pain, post-traumatic pain.
 
Items of analysis Specification Results
White to slightly yellow
crystalline powder, nearly
odorless, tasteless.
Melting point 158-162°C  158.5-160°C
Solubility
Soluble in acetone、 slightly
soluble in chloroform or ether、
methanol、ethanol, slightly
soluble in benzene, minimal
solubility in toluene, almost
insoluble in water
Identification
(1) should be positive response；
(2)Infrared absorption spectrum to control map
Chloride ≤0.02% 
Loss on drying ≤0.5% 
Residue on ignition ≤0.1%
Heavy metal ≤ 10ppm  
Assay:This product is calculated on dry product containing
( C19H16CINO4 ) shall not be less than 99%