Glucagons

Glucagons

Cas No.: 16941-32-5;9007-92-5

Molecular Formula: C₁₅₃H₂₂₅N₄₃O₄₉S

Molecular Weight：3482.74729999997

Purity (HPLC): 98.0%min.

Appearance: White powder

MS:

Glucagon generally elevates the concentration of glucose in the blood by promoting gluconeogenesis and glycogenolysis.

Glucose is stored in the liver in the form of the polysaccharide glycogen, which is a glucan (a polymer made up of glucose molecules). Liver cells (hepatocytes) have glucagon receptors. When glucagon binds to the glucagon receptors, the liver cells convert the glycogen into individual glucose molecules and release them into the bloodstream, in a process known as glycogenolysis. As these stores become depleted, glucagon then encourages the liver and kidney to synthesize additional glucose by gluconeogenesis. Glucagon turns off glycolysis in the liver, causing glycolytic intermediates to be shuttled to gluconeogenesis.

Glucagon also regulates the rate of glucose production through lipolysis. Glucagon induces lipolysis in humans under conditions of insulin suppression.

Glucagon production appears to be dependent on the central nervous system through pathways yet to be defined. In invertebrate animals, eyestalkreported to affect glucagon production. Excising the eyestalk in young crayfish produces glucagon-induced hyperglycemia.[3] removal has been

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1.      Wuhan HeZhong Bio-Chemical Manufacture Co.,Ltd is a renowned pharmaceutical manufacturer, specializing in raw steroid powders in Mainland China. It is not only   the leading manufacturer of steroids powder and pharmaceutical raw materials in the central area of China but also exports all over the world. All powders are factory directly supplying.

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