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Product name:dapoxetine
CAS No.: 119356-77-3
MF:C21H23NO
MW:341.88
Character:White to Off-White Cyrstalline Solid
Assay:99%
Brand Name: Sex Enhancers
Place of Origin: China
Standard: Enterprise Standard
Certification: ISO9001
Delivery Time: Within 24h After The Payment Confirm
Supply Ability: 500kg/month
Packaging Details: as requirement
Payment Terms: Western unio, MoneyGram, T/T
Usage:
Dapoxetine (dapoxetine) as a new fast SSRI, a short half life, a selective 5 - HT reuptake inhibitor (SSRI), for the treatment of premature ejaculation and erectile dysfunction. Dapoxetine is a selective 5 - HT reuptake inhibitor (SSRI), such drugs widely used to treat depression and related affective disorders.
Product description:
Dapoxetine, marketed as Priligy (among and other brands) is the first compound developed specially for the treatment of premature ejaculation (PE) in men 1864 years old. Dapoxetine works by inhibiting the serotonin transporter, increasing serotonin's action at the post synaptic cleft, and as a consequence promoting ejaculatory delay. As a member of selective serotonin reuptake inhibitor (SSRI) family, dapoxetine was initially created as an antidepressant. However, unlike other SSRIs, dapoxetine is absorbed and eliminated rapidly in the body. Its fast acting property makes it suitable for the treatment of PE but not as an antidepressant.
Treat male premature ejaculation and erectile dysfunction. Because lack of specific approval treatment for PE in the US and some other countries, other SSRIs such as fluoxetine, paroxetine, sertraline, fluvoxamine, and citalopram have been used as off label drugs to treat PE. Waldinger's meta analysis shows that the use of these conventional antidepressants increasing IELT from two to ninefold above base line in comparison of three to eightfold when dapoxetine is used. However, these SSRIs must be taken daily in order to achieve meaningful efficacy, and the long half-life increases the risk of the drug accumulation and as a consequence increased of adverse effects such as decreasing sexual libido and causing erectile dysfunction. Dapoxetine, on the other hand, is a fast-acting SSRI. It is rapidly absorbed and eliminated from the body within a few hours. This favorable pharmacokinetics minimizes the risk of the drug's accumulation in the body, and therefore reducing side effects.
Contact Details:
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Zhuzhou Yuancheng Hezhong Technology Development Co., Ltd.
Contact Person: Mr. Zhang Bo
Tel: +8618188938021
Fax: +86-731-22292057
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E-mail: YCWlb031@yccreate.com
