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Product Name: |
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Synonyms: |
ICI-D-1033;ARIMIDEX;1-[3,5-DI-(1-METHYL-1-CYANO)-ETHYL]-BENZYL-1,2,4-TRIAZOLE;ANASTRAZOLE;ANASTROZOLE;tetramethyl-5-(1h-1,2,4-triazol-1ylmethyl) 1,3-benzenediacetionitrile;ZD-1033;1,3-benzenediacetonitrile,alpha,alpha,alpha’,alpha’-tetramethyl-5-(1h-1,2,4-t |
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CAS: |
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MF: |
C17H19N5 |
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MW: |
293.37 |
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EINECS: |
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Product Categories: |
Active Pharmaceutical Ingredients;Antineoplastic;All Inhibitors;anti-neoplastic;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Anastrozole;API |
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Mol File: |
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mp |
81-82°C |
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storage temp. |
Store at RT |
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CAS DataBase Reference |
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Chemical Properties |
Crystalline Solid |
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Usage |
An aromatase inhibitor. Used as an antineoplastic. |
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Usage |
antiseptic, spermaticide |
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Biological Activity |
Potent and highly selective aromatase (CYP19) inhibitor (IC 50 = 15nM) that has no discernible effect on adrenocorticoid hormone synthesis. Reduces plasma estrogen levels and exhibits antitumor activity in vivo . Orally active. |

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