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Model NO.: 55-06-1
Appearance: White to Beige Powder
Molecular Formula: C15h12I3no4
Sodium L-Triiodothyronine(T3)Content (%): 99
Origin: China
Sodium L-Triiodothyronine(T3) CAS No: 55-06-1
Chemical Name: Sodium Salt, 3, 3′, 5-Triiodo-L-Thyronine
Molecular Weight: 650.97
Boiling Point: 205°c
Specification: SGS, ISO9001, KOSHER
HS Code: 2937290023
Packing:1kg/Aluminum Foil Bag or according to customer requirementsc
Storage:Store in cool & dry place not freeze., keep away from strong light and heat
Application
Liothyronine is the most potent form of thyroid hormone. Chemically, it is nearly identical to triiodothyronine (T3). As such, it acts on the body to increase the basal metabolic rate, affect protein synthesis and increase the body's sensitivity to catecholamines by permissiveness. The thyroid hormones are essential to proper development and differentiation of all cells of the human body. These hormones also regulate protein, fat, and carbohydrate metabolism, affecting how human cells use energetic compounds.
In comparison to levothyroxine (T4), liothyronine has a faster onset of action as well as a shorter biological half-life, which may be due to less plasma protein binding to thyroxine-binding globulin and transthyretin.
Physicians can use this instead of or in addition to levothyroxine (T4) for patients undergoing thyroid withdrawal. When a patient has thyroid cancer or Graves' disease, ablation therapy with radioactive iodine can be used to remove any trace thyroid tissue. For 131I therapy to be effective, the trace thyroid tissue must be avid to iodine. The best method is to starve the tissue of iodine but this can lead to hypothyroid symptoms for the patient. Withdrawal from levothyroxine can be done but it takes six weeks of withdrawal for the remaining thyroid tissue to be completely starved. Six weeks is needed owing to levothyroxine's long half life. Six weeks can be inconvenient for the patient and delay treatment. Liothyronine instead can be taken and withdrawn from for two weeks to starve the thyroid tissue. This is much safer and more convenient than levothyroxine.
