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PharmaLegacy Laboratories (Shanghai) Co., Ltd have Osteoporosis Model the important role,Osteoporosis Model latest reference price,Recommended Osteoporosis Model,The most reliable Osteoporosis Model,Newest Osteoporosis Model,Osteoporosis Model direction for use and other areas of expertise, combined with excellent service capabilities, To provide customers with professional, customized Osteoporosis Model. Moreover, since the establishment of a long time ago,the Osteoarthritis Modelbusiness of PharmaLegacy has always maintained a high-speed and stable growth. details: Bone provides protection to visceral organs, storage of minerals, locomotive movement and are the locations of hematopoiesis. Structural integrity of bone can be affected by factors of aging, dietary imbalance, disuse, environmental contamination, infections, medicine, metabolic disorders, physical loading, radiation, smoking and trauma. Efficacy and safety data of the developing therapeutics to osteoporosis model is required to predict the effects in human for excluding the toxicity of it. Bone fragility increases with age in both genders, and most notably after menopause in female. Anti-resorptive agents are well established, such as bisphosphonates, SERMs and likely anti-RANKL antibodies. Anabolic agents are actively being developed. Besides PTH analogues and stem cells, molecules from BMP family and Wnt signal pathways, such as Smads, ERK, Dkk-1, Runx2, and beta-catenin are targets for therapeutics. Safety and efficacy data of osteoporosis model (rodents and non-human primates) are required to predict the therapeutic effects in human.
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