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PharmaLegacy Laboratories (Shanghai) Co., Ltd is specialized in Business services,Medical service,Medical insurance since established in 10 years ago.So far,our company has established its branch companies in major cities throughout the country.Formed in Building 7, 388 Jialilue Road Zhangjiang High-Tech Park Pudong District Shanghai,Pudongxin District,City area,Shanghai,China as the center, the radiation sales system and service network.Details:Osteoarthritis model (OA) is a prevalent musculoskeletal disease that results in pain and low quality of life for patients, as well as enormous medical and socioeconomic burdens. The molecular mechanisms responsible for the initiation and progression of Osteoarthritis models are still poorly understood. As such, osteoarthritis model of mouse is having increasingly important roles in Osteoarthritis model research owing to the advancements of microsurgical techniques and the use of genetically modified mice, as well as the development of novel assessment tools. Osteoarthritis model, known as degenerative joint disease, involves both articular cartilage and subchondral bone. The progression of the diseased joint includes articular cartilage fibrillation, fissure and partial erosion, full thickness loss of articular cartilage and ends with bone exposed, and sclerosis of subchondral bone. Symptoms include joint pain, swelling and reduced motion in angle and extent. It can occur in any joint, but usually it affects hands, knees, hips or spine. A variety of causes – hereditary, developmental, metabolic, and mechanical – may initiate processes leading to loss of cartilage. Osteoarthritis model is the most common form of arthritis, and the leading cause of chronic disability. It affects about 40 million people in the United States.
